Benadryl and Alcohol

Mixing Benadryl and alcohol can have serious and life-threatening results

Table of Contents


Mixing alcohol and bendryl can have serious and life-threatening results. Among other things, alcohol is a powerful sedative that increases the negative effects of Benadryl. Here are the risks of mixing alcohol and Benadryl.

Damage to the Central Nervous System

The combined sedative properties of mixing alcohol and Benadryl severely impair the central nervous system. The central nervous system is in control of speech, movement, emotion, and more.

Impaired Memory

Alcohol in large quantities prohibits the forming of new memories. This effect is worsened by Benadryl which blocks certain memory related brain functions. This means mixing Benadryl and alcohol can result in blackouts and other memory conditions.

Poor Decision Making

Mixing alcohol and Benadryl prohibits higher brain function and impairs logic. Both alcohol and Benadryl have properties that can affect reasoning and when mixing alcohol and Benadryl the intensity of these properties increases.

Developing Alcohol and Drug Dependency

Mixing alcohol and Benadryl is an abuse of both substances. When these substances are consumed together there is a higher chance of developing a serious dependency.

Benadryl and Alcohol Side Effects

Alcohol and Benadryl side effects can vary but here are the most common:

Mixing alcohol and Benadryl can also irritate pre-existing health conditions like anxiety, liver conditions, and blood pressure disorders.


Alcohol and Benadryl side effects and dangers are not to be taken lightly. The undue stress on the body can result in common symptoms of dependency. Other symptoms include pale skin, stiff joints, fragile bones, malnutrition, and other compounding conditions. Alcohol and Benadryl side effects are worsened when taken in conjunction with other medication. Mixing alcohol and Benadryl is not recommended.

Can You Die from Benadryl and Alcohol?

Mixing alcohol and Benadryl can cause the body to go into any number of life-threatening states. Here are two of the most common:

Cardiac Arrest

Cardiac arrest can occur due to the effects of Benadryl on the central nervous system. Symptoms of cardiac arrest include chest pain, shortness of breath, abdominal cramps, and loss of consciousness. Cardiac arrest requires immediate hospitalization.

Alcohol Poisoning

Alcohol and Benadryl impair the liver’s ability to process chemicals. This results in a higher blood alcohol levels and long-term liver damage. Symptoms of alcohol poisoning include vomiting, seizures, shortness of breath, loss of conscious and severe confusion. Death from mixing alcohol and Benadryl can be prevented by seeking help. It also important for the public perception of drug and alcohol dependency to change for society to acknowledging and addressing potential dependency.

Benadryl and Alcohol Treatment

If you or anyone you know is in need of alcohol and benadryl treatment then reach out to your local clinics and centers for more information.


If you or a loved one needs help, please call us at
623-523-4748 and our team at Blueprints For Recovery in Arizona will help.

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